valvular lesion造句

• This fraction affords a quantitative measure of the severity of the valvular lesion.
• In patients with severe valvular lesions, regurgitant fraction can approach 80 %.
• Rheumatic valvular lesions may also involve a cell-mediated immunity reaction as these lesions predominantly contain T-helper cells and macrophages.
• Valvular disease is caused primarily by valvular lesions stemming from infections, especially rheumatic fever ( Streptococceus pyogenes ), which can result in either a regurgitant or stenotic valve, or both.
• Human leukocyte antigen ( HLA ) class II allele DR7 ( HLA-DR7 ) is most often associated with RHD, and its combination with certain DQ alleles is seemingly associated with the development of valvular lesions.